WebA-kinase interacting protein 1 might serve as a novel biomarker for worse prognosis through the interaction of chemokine (C-X-C motif) ligand 1/chemokine (C-X-C motif) ligand 2 in acute myeloid leukemia. 14-3-3zeta-TRAF5 axis governs interleukin-17A signaling. Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages
Noncanonical Pathway for Regulation of CCL2 Expression by an
WebApr 4, 2024 · The CC chemokine ligand 2 (CCL2), a member of the CC chemokine family, is a chemoattractant for monocytes and T cells through interaction with its receptor CCR2. MCP-1 interactions with chemokine receptor CCR2 are required for optimal macrophage recruitment and MIP-1 alpha production, natural killer cell accumulaton, IFN-gammma … care homes blaydon
Ccl12 MGI Mouse Gene Detail - MGI:108224 - chemokine (C-C motif) ligand …
WebApr 8, 2024 · CAFs regulate tumor cell phenotype, metastasis and angiogenesis via releasing growth factors, pro-inflammatory cytokines and chemokines including C–X–C motif chemokine ligand 12 (CXCL12) [16, 17], which is robustly expressed in most cancers, and plays important roles in cancer growth, migration, invasion and angiogenesis [18,19,20]. WebJan 13, 2024 · The chemokine ligand CCL2 and its receptor CCR2 are implicated in the initiation and progression of various cancers. CCL2 can activate tumour cell growth and proliferation through a variety of ... WebCCL2 signals to these target cell types by binding to and activation of the seven transmembrane G-protein-coupled receptor C–C chemokine receptor type 2 (CCR2) ( 47 ). Several intracellular downstream signaling … brookshire brothers pharmacy newton tx