WebApr 10, 2024 · To measure the degree to which liver-wide Mboat7 deletion promotes fatty liver disease, we used a high dose of adeno-associated virus serotype 8 (AAV8)-TBG-Cre to generate liver-wide knockout (KO) mice. We observed efficient deletion of the floxed exon and depletion of the intact Mboat7 mRNA (Figures S1A and S1B) after WebApr 30, 2024 · Cre/loxP Recombination System: Applications, Best Practices, and Breeding Strategies. Site-specific recombinases represent one of the most versatile tools available …
Hepatocyte-specific knockout of HIF-2α cannot alleviate …
WebAug 6, 2024 · Cre-lox mice are made from crossing a strain that expresses Cre with a strain that expresses a floxed gene of interest. Cre may be expressed globally (in every cell of the mouse) or in a tissue-specific manner (with expression controlled by a … WebApr 10, 2024 · HIGHLIGHTS who: Hengjun Huang from the Mice and immunization All experimental animal operations were approved by the Institutional Animal Care and Use Committee of the Southern University of Science and … The rna-binding protein hnrnp f is required for the germinal center b cell response Read Research » the meaning of the name zayd
Cre-Lox Recombination System & Conditional Mouse Models
WebApr 12, 2024 · We delivered chicken DF1 cells producing four viruses encoding P1 bacteriophage Cre recombinase, human H3.3K27M, murine platelet-derived growth factor B ... (CNS). Moreover, single knockout H3f3a or H3f3b male and female mice are normal and fertile; only double-knockout mice show developmental retardation and embryonic … WebCre-Lox recombination is a site-specific recombinase technology, used to carry out deletions, insertions, translocations and inversions at specific sites in the DNA of cells. It allows the DNA modification to be targeted to a specific cell type or be triggered by a specific external stimulus. It is implemented both in eukaryotic and prokaryotic ... the meaning of the name ziva